Author

Alison K. McClellan

Stanford Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Austin HartmaniD· 3 shared Courtney KernickiD· 3 shared Johnathan Lu· 3 shared Nicole E. Theberath· 3 shared Oliver Takacsi-Nagy· 3 shared Theodore L. RothiD· 3 shared Andy Y. CheniD· 2 shared Ansuman T. SatpathyiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Austin HartmanORCID

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3 papers

Recent·Most cited

Ultra-large targeted DNA integrations in primary human cells

Courtney Kernick, Lauren Chow, Mikail Alejandro, Ke Li, Maxwell Gabriel Foisey, Xiaoyu Yang, Claire E. Hilburger, Johnathan Lu, Lujing Wu, Alison K. McClellan, Oliver Takacsi-Nagy, Rocco Brajenovic, Nicole E. Theberath, Emily Celallos Fuentes, Erin Lin, , Theodore L. Roth

This paper identifies methods to achieve ultra-large DNA integrations (>10 kb) in human cells with high efficiency using optimized templates and delivery strategies.

bioRxiv · Apr 9, 2026 · PreprintGenetics

A unified genetic perturbation language for human cellular programming

Austin Hartman, Oliver Takacsi-Nagy, Courtney Kernick, Nicole E. Theberath, Johnathan Lu, Lujing Wu, Michelle Mantilla, Siddhesh Mittra, Alison K. McClellan, Nicole Johnson, Lina Mohamad, Lesly Castillo-Colin, Farzad Hoque, Alexander Eapen, Andy Y. Chen, , Theodore L. Roth

CRISPR-All enables genome-scale, combinatorial genetic perturbations in human cells, revealing additive functional improvements through multiplexed modifications.

bioRxiv · Nov 20, 2025 · PreprintGenetics

Evolutionarily guided transcription factor design programs novel T cell states

Oliver Takacsi-Nagy, Austin Hartman, Andy Y. Chen, Yajie Yin, Gabriella C. Reeder, Courtney Kernick, Johnathan Lu, Alison K. McClellan, Colin J. Raposo, Nicole E. Theberath, Patrick Yan, Justin Eyquem, Theodore L. Roth, Ansuman T. Satpathy

This paper designs novel transcription factors using evolutionary principles to generate T cell states with enhanced functionality.

bioRxiv · Nov 6, 2024 · PreprintGenetics