FOLR1-targeted Actinium-225-based Alpha-particle Therapy Eliminates Ovarian Cancer
Neetu Singh, Esther Need, Ayden Berndt, Matthew Goff, Lydia J. Wilson, Firas Mourtada, Feng Guo, Tara Mastren, Taslim Ahmed Al-Hilal, Anil K. Sood, Amit M. Maity, Scott C. Miller, Satoshi Minoshima, Shreya Goel, Sixiang Shi
This study demonstrates that FOLR1-targeted Actinium-225 alpha-particle therapy effectively treats ovarian cancer with high tumor regression and survival rates while minimizing toxicity.
Science Advances · Jun 24, 2026Peer-reviewedBioengineering