Author

Feng Yan

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alan S. Fanning· 1 shared Chen Ruiting· 1 shared Dennis GoldfarbiD· 1 shared FANG Chenjie· 1 shared JIAN Shuling· 1 shared Mark A. PeiferiD· 1 shared Mengzhu Yuan· 1 shared Michael B. MajoriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

Alan S. Fanning

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Author profile →

3 papers

Recent·Most cited

Aberrant 5-Methylcytosine tRNA Modification Disrupts Proteostasis and Exacerbates Age-Related Osteoporosis

Zhuolin Peng, Ning Peng, Mengzhu Yuan, Feng Yan, Tie-Jian Jiang, Mingsheng Ye, Ye Xiao

This study shows that reduced tRNA m5C modification due to Nsun2 downregulation disrupts proteostasis and worsens age-related osteoporosis, with potential therapeutic benefits from molecular chaperone activators.

bioRxiv · Nov 4, 2025 · PreprintCell Biology

Proximity proteomics provides a new resource for exploring the function of Afadin and the complexity of cell-cell adherens junctions

Wangsun Choi, Dennis Goldfarb, Feng Yan, Michael B. Major, Alan S. Fanning, Mark A. Peifer

The paper uses proximity proteomics to identify proteins interacting with Afadin in MDCK cells, revealing new adherens junction components and their overlap with other junctions.

Biology Open · Jan 30, 2025Peer-reviewedCell Biology

Development of a cell-based DIFF-rGFP assay system for generalized discovery of viral protease Inhibitors

Xiaoyan Wu, Feng Yan, Chen Ruiting, FANG Chenjie, Wang Shuai, Sun huimin, JIAN Shuling, Song jiiasheng, Wu Beibei

The paper develops a cell-based DIFF-rGFP assay system for screening viral protease inhibitors, demonstrating its effectiveness in identifying novel antivirals against SARS-CoV-2.

bioRxiv · Feb 1, 2024 · PreprintMolecular Biology