Author

Tie-Jian Jiang

Central South UniversityORCID 0000-0003-0841-7962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Feng Yan· 1 shared Mengzhu Yuan· 1 shared Mingsheng Ye· 1 shared Ning PengiD· 1 shared Ye XiaoiD· 1 shared Zhuolin Peng· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

Feng Yan

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintNov 4, 2025

Aberrant 5-Methylcytosine tRNA Modification Disrupts Proteostasis and Exacerbates Age-Related Osteoporosis

Zhuolin Peng, Ning Peng, Mengzhu Yuan…·Ye Xiao

This study shows that reduced tRNA m5C modification due to Nsun2 downregulation disrupts proteostasis and worsens age-related osteoporosis, with potential therapeutic benefits from molecular chaperone activators.

DOI 10.1101/2025.11.04.686482

mouseproteomics

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