Author

Ye Xiao

Central South UniversityORCID 0000-0002-5876-4367Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Feng Yan· 1 shared Mengzhu Yuan· 1 shared Mingsheng Ye· 1 shared Ning PengiD· 1 shared Qi GuoiD· 1 shared Tie-Jian JiangiD· 1 shared Wen-Feng XiaoiD· 1 shared Yu-Jue Li· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

Feng Yan

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2 papers

Recent·Most cited

Aberrant 5-Methylcytosine tRNA Modification Disrupts Proteostasis and Exacerbates Age-Related Osteoporosis

Zhuolin Peng, Ning Peng, Mengzhu Yuan, Feng Yan, Tie-Jian Jiang, Mingsheng Ye, Ye Xiao

This study shows that reduced tRNA m5C modification due to Nsun2 downregulation disrupts proteostasis and worsens age-related osteoporosis, with potential therapeutic benefits from molecular chaperone activators.

bioRxiv · Nov 4, 2025 · PreprintCell Biology

RNA-binding protein YBX1 promotes Type H vessels dependent bone formation in an m5C-dependent manner

Yu-Jue Li, Qi Guo, Wen-Feng Xiao, Ye Xiao

This study shows that YBX1 promotes bone formation through m5C-dependent regulation of CD31, EMCN, and BMP4 in endothelial cells, offering a therapeutic target for osteoporosis.

bioRxiv · Apr 21, 2023 · PreprintMolecular Biology