The trimeric structures of the extracellular domains of FAM171A1 and FAM171A2 neuronal proteins belong to a novel structural superfamily
Thomas W. Bird, Sepideh Valimehr, David M. Wood, Zachary D. Tillett, Leanid Kresik, Gerd Mittelstädt, Florian De Pol, Dimphna H. Meijer, Renwick C. J. Dobson, Joris de Wit, Eric G. Hanssen, Davide Comoletti
This study determines the trimeric structures of FAM171A1 and FAM171A2 extracellular domains, revealing a novel structural superfamily and their oligomerization properties.
bioRxiv · Sep 18, 2025 · PreprintNeuroscience