Author

Florian Lesage

IPMC;Primary ORCID profile (0000-0002-4406-7106 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Florian LesageiD3 papers · Centre National de la Recherche Scientifique

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aline Rio· 1 shared Barbara Ribeiro de Oliveira MendesiD· 1 shared Béatrice Olivier· 1 shared Gildas LoussouarniD· 1 shared Jérome MontnachiD· 1 shared Malak AlamehiD· 1 shared Marja Steenman· 1 shared Michel De WaardiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Aline Rio

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Author profile →

1 paper

Recent·Most cited

Expression-System Biases Compromise the Functional Assessment of KCNH2 Variants and Clinical Risk Assessment

Aline Rio, Malak Alameh, Sylvain Feliciangeli, Rita Semaan, Marja Steenman, Béatrice Olivier, Jérome Montnach, Florian Lesage, Barbara Ribeiro de Oliveira Mendes, Michel De Waard, Gildas Loussouarn

This study shows that common dual-expression systems fail to balance WT and variant hERG expression, leading to inaccurate functional assessments of KCNH2 variants.

bioRxiv · Nov 10, 2026 · PreprintBiophysics