Author

Malak Alameh

Centre National de la Recherche ScientifiqueORCID 0009-0000-3839-9828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1

Frequent Co-Authors

Bárbara Bruna Ribeiro Oliveira-MendesiD· 2 shared Gildas LoussouarniD· 2 shared Jérome MontnachiD· 2 shared Michel MDW DE WAARDiD· 2 shared Achille Gregoire· 1 shared Aline Rio· 1 shared Aurélie TholletiD· 1 shared Béatrice Olivier· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

Bárbara Bruna Ribeiro Oliveira-MendesORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 10, 2026

Expression-System Biases Compromise the Functional Assessment of KCNH2 Variants and Clinical Risk Assessment

Aline Rio, Malak Alameh, Sylvain Feliciangeli…·Gildas Loussouarn

This study shows that common dual-expression systems fail to balance WT and variant hERG expression, leading to inaccurate functional assessments of KCNH2 variants.

DOI 10.64898/2026.11.04.764433

humanbulk RNA-seq

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BiophysicsbioRxivPreprintMay 4, 2026

MeTAL enables multiparametric risk prediction for human KCNH2 variants

Bárbara Bruna Ribeiro Oliveira-Mendes, Elouan Voisin, Maxence Marbouty…·Rupamanjari Majumder

MeTAL links KCNH2 variant biophysical properties to ECG phenotypes, revealing nonlinear relationships and improving risk prediction for inherited arrhythmia syndromes.

DOI 10.64898/2026.04.29.721778

humanelectrophysiology

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