BIOFABRICATION OF AN OVINE INTERVERTEBRAL DISC MODEL BY COMBINING A POLYCAPROLACTONE FRAME WITH A BIOPRINTED ALGINATE HYDROGEL
Emmaëlle Carrot, Mansoor Chaaban, Daronne Cano Contreras, Clara Schiex, Joëlle Véziers, Boris Halgand, François Loll, Johann Clouet, Michael G. Monaghan, Marion Fusellier, Jérôme Guicheux, Vianney Delplace, Catherine Le Visage
This paper develops a 3D in vitro model of an ovine intervertebral disc using a PCL frame and alginate hydrogel, demonstrating effective cell alignment and phenotype preservation.
Biofabrication · Sep 26, 2025Peer-reviewedBioengineering