Catherine Le Visage

The paper develops a microfluidic method to encapsulate stem cell spheroids and nanomedicines in alginate beads to enhance cell viability and therapeutic potential.

This paper compares transcriptomic and functional differences between healthy and degenerated ovine intervertebral disc cells, finding age-related inflammatory and senescence signatures and shared transcriptional modules with human degenerated discs.

This paper develops a degradable PCLA nanofibrous scaffold for annulus fibrosus repair, showing accelerated degradation and tissue regeneration in ovine models.

This paper develops a 3D in vitro model of an ovine intervertebral disc using a PCL frame and alginate hydrogel, demonstrating effective cell alignment and phenotype preservation.

This study develops covalent alginate hydrogels using SPAAC cross-linking for encapsulating human adipose MSCs, demonstrating their viability and immunomodulatory activity in vitro.