Pentatricopeptide repeat poly(A) binding protein from mitochondria of trypanosomes
Mikhail V. Mesitov, Tian Yu, Takuma Suematsu, Francois M. Sement, Liye Zhang, Clinton Yu, Lan Huang, Inna Aphasizheva
The paper identifies KPAF4, a mitochondrial PABP in Trypanosoma brucei, which regulates mRNA editing and 3' modification by preventing premature A/U-tailing and ensuring transcript stability.
bioRxiv · Oct 29, 2018 · PreprintBiochemistry