Polo kinase phosphorylation determines C. elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation
Oliver Wueseke, David Zwicker, Anne Schwager, Yao Liang Wong, Karen Oegema, Frank Julicher, Anthony A Hyman, Jeffrey Woodruff
This study shows Polo kinase phosphorylation accelerates SPD-5 scaffold assembly in C. elegans centrosomes, determining PCM size and density, but not scaffold maintenance.
bioRxiv · Aug 1, 2016Cell Biology