Author

Oliver Wueseke

System Biosciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alex A. PolleniD· 1 shared Alex RogozhnikoviD· 1 shared Andy Lash· 1 shared Anne Schwager· 1 shared Anthony A Hyman· 1 shared Anthony Batarse· 1 shared Anthony Bosshardt· 1 shared Arden B. PiephoiD· 1 shared

Activity by Year

2016-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alex A. PollenORCID

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Author profile →

2 papers

Recent·Most cited

Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease

Kevan D. Shah, Rishi Bedi, Alex Rogozhnikov, Pavan Ramkumar, Zhixiang Tong, Brian G. Rash, Morgan M. Stanton, Jordan M. Sorokin, Cagsar Apaydin, Anthony Batarse, Julia Bergamaschi, Robert M. Blattner, Spencer Brown, Anthony Bosshardt, Carlos Castrillo, , G. Sean Escola

This paper develops an automated system to scale patient-derived brain organoids, revealing consistent donor and batch effects and demonstrating reproducible disease phenotypes in tuberous sclerosis models.

bioRxiv · Aug 26, 2020 · PreprintNeuroscience

Polo kinase phosphorylation determines C. elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation

Oliver Wueseke, David Zwicker, Anne Schwager, Yao Liang Wong, Karen Oegema, Frank Julicher, Anthony A Hyman, Jeffrey Woodruff

This study shows Polo kinase phosphorylation accelerates SPD-5 scaffold assembly in C. elegans centrosomes, determining PCM size and density, but not scaffold maintenance.

bioRxiv · Aug 1, 2016Cell Biology