Disrupted Lipid Homeostasis as a Pathogenic Mechanism in ABCA7-Associated Alzheimers Disease Risk
Younji Nam, Brooke A. DeRosa, Aura María Ramírez, Biniyam A. Ayele, Patrice L. Whitehead, Larry Deon Adams, Charles G. Golightly, Takiyah D. Starks, Mayra Juliana Laverde-Paz, Holly N. Cukier, Rufus Akinyemi, Fred Sarfo, Albert Kwaku Akpalu, Michael L. Cuccaro, Scott M. Williams, , Margaret Ann Pericak‐Vance
This paper investigates the impact of an ancestry-specific ABCA7 deletion on lipid homeostasis in Alzheimer's disease, showing disrupted lipid regulation in neurons.
Alzheimer s & Dementia · Mar 30, 2026Peer-reviewedNeuroscience