Local genetic correlation analysis of Alzheimer's disease and stroke implicates PHLPP1 as a shared locus in individuals of African ancestry
Nicholas R. Ray, Jiji Thulaseedhara Kurup, Ajneesh Kumar…·Christiane Reitz
Author
University of IbadanORCID 0000-0001-5286-428XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
9 papers
Recent·Most cited
Nicholas R. Ray, Jiji Thulaseedhara Kurup, Ajneesh Kumar…·Christiane Reitz
Younji Nam, Brooke A. DeRosa, Aura María Ramírez…·Margaret Ann Pericak‐Vance
This paper investigates the impact of an ancestry-specific ABCA7 deletion on lipid homeostasis in Alzheimer's disease, showing disrupted lipid regulation in neurons.
Fulya Akçimen, Kimberly Paquette, Peter Wild Crea…·Kamalini Ghosh Galvelis
This study identifies genetic variants associated with Parkinson's disease in African and African admixed populations, highlighting differences from European and Asian populations.
Shiying Liu, William S. Bush, Rufus Akinyemi…·Dana C. Crawford
This study reviews heritability estimates for late-onset Alzheimer's disease, showing significant variation across studies and highlighting the importance of population and methodological context.
Moustafa I Morsy, Fred Stephen Sarfo, Osahon Jeffery Asowata…·Mayowa Ojo Owolabi
The paper investigates the association between inflammatory biomarkers, stroke severity, and outcomes in indigenous Africans using data from the SIREN cohort.
Guido J. Falcone, Stacey Q Wolfe, Marialuisa Zedde…·the ERICH-Gene Investigators
ERICH-GENE collects and analyzes genomic and neuroimaging data from over 10,000 multi-ethnic ICH cases to identify genetic risk factors and trans-ethnic variation in ICH.
Nicholas R. Ray, Brian W. Kunkle, Kara L. Hamilton‐Nelson…·Christiane Reitz
Mie Rizig, Sara Bandrés‐Ciga, Mary B. Makarious…·Francis Ojini
Intronic GBA1 variant rs3115534-G, common in African and African admixed ancestry but rare elsewhere, raises Parkinson's disease risk (OR 1.58) and lowers onset age.
Olaitan Okunoye, Oluwadamilola Omolara Ojo, Oladunni Abiodun…·Njideka Ulunma Okubadejo
The paper examines MAPT haplotype frequencies in Nigerian Africans and finds no association between the H1 haplotype and Parkinson's disease risk or age at onset.