Remodeling of KRAS interactome induced by clinically relevant RAS inhibitors reveals convergent responses and a KRAS-mediated regulation of directional cell migration
Yang Yang, Charles Y. Cho, Ansgar Brock, Doug Quackenbush, Kaisheng Chen, Frederick Lo, Cyril H. Benes, Jacob R. Haling
This study examines how RAS inhibitors alter the KRAS interactome, revealing shared responses and a role for KRAS in regulating directional cell migration.
bioRxiv · Nov 14, 2025 · PreprintCancer Biology