Author

Cyril H. Benes

Harvard UniversityORCID 0000-0002-8751-9707Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

Alexandra PopaiD· 1 shared Anish ThomasiD· 1 shared Ansgar BrockiD· 1 shared Augustin LunaiD· 1 shared Charles Y. Cho· 1 shared Chris SanderiD· 1 shared Cristina Rosa FerroneiD· 1 shared David E. RootiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

Alexandra PopaORCID

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Author profile →

3 papers

Recent·Most cited

Remodeling of KRAS interactome induced by clinically relevant RAS inhibitors reveals convergent responses and a KRAS-mediated regulation of directional cell migration

Yang Yang, Charles Y. Cho, Ansgar Brock, Doug Quackenbush, Kaisheng Chen, Frederick Lo, Cyril H. Benes, Jacob R. Haling

This study examines how RAS inhibitors alter the KRAS interactome, revealing shared responses and a role for KRAS in regulating directional cell migration.

bioRxiv · Nov 14, 2025 · PreprintCancer Biology

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets

Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qibiao Wu, Yuanli Zhen, Robert Tyler Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, , Nabeel M. Bardeesy

This study creates a biliary tract cancer cell line atlas using multi-omics data to identify molecular subtypes and therapeutic targets.

Cancer Discovery · May 12, 2025Peer-reviewedCancer Biology

Integrative analysis of pharmacogenomics in major cancer cell line databases using CellMinerCDB

Vinodh N. Rajapakse, Augustin Luna, Mihoko Yamade, Lisa Loman, Sudhir Varma, Margot Sunshine, Francesco Iorio, Fabrício Garmus Sousa, Fathi Elloumi, Mirit I. Aladjem, Anish Thomas, Chris Sander, Kurt W. Kohn, Cyril H. Benes, Mathew J. Garnett, , Yves G. Pommier

CellMinerCDB integrates pharmacogenomic data from multiple cancer cell line databases to identify drug response determinants, reproducibility, and novel genomic signatures.

bioRxiv · Apr 2, 2018 · PreprintBioinformatics