Peroxiredoxin 1 safeguards the nucleolar genome from oxidative damage
Takashi Furusawa, Vaibhavi V. Gujar, Shalu Sharma, Frimpong Boateng, Haojian Li, Cyrinne Achour, Daiki Taniyama, Yves G. Pommier, Shalini Oberdoerffer, Travis H. Stracker, Urbain Weyemi
This study identifies PRDX1's role in preventing oxidative damage to the nucleolar genome by maintaining rDNA transcription and ribosome biogenesis.
bioRxiv · Nov 12, 2025 · PreprintMolecular Biology