Shalini Oberdoerffer

This study identifies EOLA1 as a deacetylase that recycles N4-acetylcytidine (acC) in nucleotide salvage, revealing a pathway for modified nucleotide recycling relevant to therapeutic RNA design.

This study identifies PRDX1's role in preventing oxidative damage to the nucleolar genome by maintaining rDNA transcription and ribosome biogenesis.

The paper shows that codon usage and amino acid identity significantly influence mRNA stability in humans, affecting protein abundance through translational elongation rates.

The paper shows that 5caC enhances CTCF binding to suboptimal sequences and identifies ~13,000 new CTCF binding sites in a cellular model with high 5caC levels.

The paper investigates the relationship between pre-mRNA splicing and DNA methylation using an isogenic minigene resource and finds they are independent.