Author

Takashi Furusawa

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alexei V. LobanoviD· 2 shared Urbain WeyemiiD· 2 shared Vaibhavi V. GujariD· 2 shared Yves G. PommieriD· 2 shared Bhavishya Ramamoorthy· 1 shared Chandrayee GhoshiD· 1 shared Chi‐Ping DayiD· 1 shared Cyrinne AchouriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Alexei V. LobanovORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CRISPR-Based Gene Dependency Screens reveal Mechanism of BRAF Inhibitor Resistance in Anaplastic Thyroid Cancer

Shawn Noronha, Yue Liu, Geneti Gaga, Hongchuan Li, Xiao‐Lin Wu, David Sun, Vaibhavi V. Gujar, Takashi Furusawa, Alexei V. Lobanov, Maggie C. Cam, Lipika R. Pal, Nishanth Ulhas Nair, Chi‐Ping Day, Eytan Ruppin, Chandrayee Ghosh, , Myriem Boufraqech

This study identifies TAZ deficiency as synthetically lethal with BRAF inhibitors in anaplastic thyroid cancer, revealing a mechanism of resistance and a potential therapeutic target.

Molecular Carcinogenesis · Apr 26, 2026Peer-reviewedCancer Biology

Peroxiredoxin 1 safeguards the nucleolar genome from oxidative damage

Takashi Furusawa, Vaibhavi V. Gujar, Shalu Sharma, Frimpong Boateng, Haojian Li, Cyrinne Achour, Daiki Taniyama, Yves G. Pommier, Shalini Oberdoerffer, Travis H. Stracker, Urbain Weyemi

This study identifies PRDX1's role in preventing oxidative damage to the nucleolar genome by maintaining rDNA transcription and ribosome biogenesis.

bioRxiv · Nov 12, 2025 · PreprintMolecular Biology

H3K27 Acetylated Nucleosomes Facilitate HMGN Protein Localization at Regulatory Sites to Modulate The Interaction of Transcription Factors with Chromatin

Shaofei Zhang, Yuri V. Postnikov, Alexei V. Lobanov, Takashi Furusawa, Tao Deng, Michael Bustin

The paper shows HMGN proteins bind to H3K27ac nucleosomes at regulatory sites, modulating transcription factor-chromatin interactions and gene expression.

Communications Biology · Feb 23, 2022Peer-reviewedMolecular Biology