Nutrient limitation magnifies fitness costs of antimalarial drug resistance mutations
S. K. Nair, X. Li, G. A. Arya, M. McDew-White, M. Ferrari, T. J. Anderson
This study shows that fitness costs of antimalarial drug resistance mutations are significantly higher in nutrient-limited media compared to standard RPMI, suggesting underestimation in typical lab conditions.
bioRxiv · Aug 2, 2021Microbiology