Author

G. B. Githure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

V. Ober· 2 shared D. Zilberstein· 1 shared E. Lorentzen· 1 shared E. Polatoglou· 1 shared F. Schwede· 1 shared G. Moya· 1 shared I. Q. Phan· 1 shared J. Basquin· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

V. Ober

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

V. Ober, G. B. Githure, Y. Volpato Santos, S. Becker, G. Moya, J. Basquin, F. Schwede, E. Lorentzen, M. Boshart

This study identifies natural nucleosides as activators of PKA in trypanosomatid pathogens, showing they replace cAMP in allosteric regulation through specific binding to CNB domains.

bioRxiv · Oct 24, 2023Biochemistry

A divergent protein kinase A in the human pathogen Leishmania is associated with cell cortex microtubules and controls cell shape

R. Fischer-Weinberger, S. Bachmaier, V. Ober, G. B. Githure, R. Dandugudumuoa, I. Q. Phan, M. Almoznino, E. Polatoglou, P. Tsigankove, R. Nitzan Koren, P. J. Myler, M. J. Boshart, D. Zilberstein

This paper identifies a novel PKA regulatory subunit in Leishmania that localizes to microtubules and controls promastigote shape by tethering the catalytic subunit to the cell cortex.

bioRxiv · Apr 24, 2021 · PreprintCell Biology