Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages
J. Yang, D. Mott, R. Sutiwisesak, Y. J. Lu, F. Rosa, B. Stowell, G. Babunovic, J. Lee, S. Carpenter, S. S. Way, S. Fortune, S. M. Behar
This study compares CD4+ and CD8+ T cell recognition of Mtb-infected macrophages, finding CD8+ T cells poorly recognize infected macrophages despite strong immunodominant responses.
bioRxiv · Feb 20, 2018Immunology