A Structural Ensemble of a Tau-Microtubule Complex Reveals Regulatory Tau Phosphorylation and Acetylation Mechanisms
Z. F. Brotzakis, P. Lindstedt, R. Taylor, G. Bernardes, M. Vendruscolo
The paper determines the structural ensemble of a tau-microtubule complex using cryo-EM, revealing phosphorylation and acetylation sites that destabilize the complex.
bioRxiv · Nov 10, 2020Biophysics