Author

G. Byrne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. Yu· 2 shared P. W. Berman· 2 shared S. M. O'Rourke· 2 shared D. Alexander· 1 shared D. L. Alexander· 1 shared K. A. Mesa· 1 shared M. Wright· 1 shared P. Azadi· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

B. Yu

Mutual co-authors in cluster

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2 papers

Recent·Most cited

CRISPR/Cas9 gene editing for the creation of an MGAT1 deficient CHO cell line to control HIV-1 vaccine glycosylation

G. Byrne, S. M. O'Rourke, D. L. Alexander, B. Yu, R. Doran, M. Wright, Q. Chen, P. Azadi, P. W. Berman

This paper develops a CRISPR/Cas9-edited CHO cell line deficient in MGAT1 to produce HIV-1 gp120 with early glycosylation intermediates, enhancing binding to glycan-dependent broadly neutralizing antibodies.

bioRxiv · Jul 13, 2018Bioengineering

Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine for production

S. M. O'Rourke, G. Byrne, T. Gwen, W. Meredith, B. Yu, K. A. Mesa, R. C. Doran, D. Alexander, P. W. Berman

This paper develops a gene-edited CHO cell line and robotic selection method to improve Env expression and antigenic structure for HIV vaccine production.

bioRxiv · May 8, 2018Bioengineering