Author

G. D. D. Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Cooper· 1 shared C. Toffanin· 1 shared D. Ebner· 1 shared E. Seraia· 1 shared F. A. Okonjo· 1 shared F. Buffa· 1 shared H. H. K. Abbas· 1 shared K. A. Lopez· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

C. Cooper

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Therapeutic targeting of SETD2-deficient cancer cells with the small-molecule compound RITA

K. A. Lopez, S. Sarkar, E. Seraia, C. Toffanin, C. Cooper, M. Challoumas, F. A. Okonjo, G. D. D. Jones, F. Buffa, D. Ebner, T. C. Humphrey

This paper identifies RITA as a compound that selectively kills SETD2-deficient cancer cells by inducing p53-mediated apoptosis and replication stress.

bioRxiv · Jul 8, 2021 · PreprintCell Biology

MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?

H. H. K. Abbas, K. M. H. Alhamoudi, M. D. Evans, G. D. D. Jones, S. S. Foster

This study investigates MTH1's role in lung cancer cells, finding that its deficiency increases oxidative DNA damage but does not enhance cytotoxicity or response to standard therapies.

BMC Cancer · Apr 16, 2018Peer-reviewedCancer Biology