CARD9 in Neutrophils Protects from Colitis and Controls Mitochondrial Metabolism and Cell Survival
C. Danne, C. Michaudel, J. Skerniskyte, J. Planchais, A. Magniez, A. Agus, M.-L. Michel, B. Lamas, G. Da-Costa, M. Spatz, C. Oeuvray, C. Galbert, M. Poirier, Y. Wang, A. Lapiere, , H. Sokol
This study identifies CARD9's protective role in neutrophils against colitis by maintaining mitochondrial function and cell survival, revealing a mechanism for intestinal inflammation control.
bioRxiv · Jan 14, 2022Immunology