Author

H. Sokol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

C. Danne· 2 shared C. Galbert· 2 shared C. Oeuvray· 2 shared N. Rolhion· 2 shared P. Langella· 2 shared T. Ledent· 2 shared A. Agus· 1 shared A. Bhargava· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

C. Danne

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Regulation of Lung Immune Tone by the Gut-Lung Axis via Dietary Fiber, Gut Microbiota, and Short-Chain Fatty Acids

D. Maruyama, W.-I. Liao, X. Tian, M. Bredon, J. Knapp, T. Doan, C. Tat, B. Chassaing, A. Bhargava, H. Sokol, A. Prakash

This study shows that dietary fiber and gut microbiota influence lung immune tone via short-chain fatty acids, reducing inflammation and lung injury in mice.

bioRxiv · Aug 24, 2023 · PreprintImmunology

A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates

S. Pons, E. Frapy, Y. Sereme, C. Gaultier, F. Lebreton, A. Kropec, O. Danilchanka, L. Schlemmer, C. Schrimpf, M. Allain, F. Angoulvant, H. Lecuyer, S. Bonacorsi, H. Aschard, H. Sokol, , D. Skurnik

This study uses TnSeq to identify E. coli K1 genes important for meningitis, focusing on PNAG as a vaccine target, showing its efficacy against E. coli and Group B Streptococcus in neonatal models.

bioRxiv · Dec 22, 2022Microbiology

Human CD4+/CD8α+ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation

S. Touch, E. Godefroy, N. Rolhion, C. Danne, C. Oeuvray, M. Straube, C. Galbert, L. Brot, I. Alonso Salgueiro, S. Chadi, T. Ledent, J. M. Chatel, P. Langella, F. Jotereau, F. Altare, H. Sokol

The paper shows that human CD4+/CD8α+ regulatory T cells induced by Faecalibacterium prausnitzii reduce intestinal inflammation in a mouse model and correlate with disease activity in IBD patients.

bioRxiv · Mar 22, 2022Immunology

CARD9 in Neutrophils Protects from Colitis and Controls Mitochondrial Metabolism and Cell Survival

C. Danne, C. Michaudel, J. Skerniskyte, J. Planchais, A. Magniez, A. Agus, M.-L. Michel, B. Lamas, G. Da-Costa, M. Spatz, C. Oeuvray, C. Galbert, M. Poirier, Y. Wang, A. Lapiere, , H. Sokol

This study identifies CARD9's protective role in neutrophils against colitis by maintaining mitochondrial function and cell survival, revealing a mechanism for intestinal inflammation control.

bioRxiv · Jan 14, 2022Immunology

The enemy from within: a prophage of Roseburia intestinalis systematically turns lytic in the mouse gut, driving bacterial adaptation by CRISPR spacer acquisition

J. K. Cornuault, E. Moncaut, V. Loux, A. Mathieu, H. Sokol, M.-A. Petit, M. De Paepe

This study shows prophages in Roseburia intestinalis become lytic in the mouse gut, driving bacterial adaptation through CRISPR spacer acquisition and phage resistance.

bioRxiv · Mar 13, 2019Microbiology