Author

G. Drewes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Brown· 1 shared A. H. Smits· 1 shared A.-M. Michon· 1 shared C. Garro· 1 shared D. Eberhard· 1 shared F. Ziebell· 1 shared G. Joberty· 1 shared G. Soria· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Brown

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Author profile →

2 papers

Recent·Most cited

Inhibitors of ROCK kinases induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells

J. Martino, S. O. Siri, N. S. Paviolo, C. Garro, M. F. Pansa, S. Carbajosa, A. Brown, J. L. Bocco, I. Gloger, G. Drewes, K. P. Madauss, G. Soria, V. Gottifredi

This paper shows that ROCK kinase inhibitors induce synthetic lethality in BRCA2-deficient cells through mitotic defects, independent of DNA damage.

bioRxiv · Jun 24, 2022Cancer Biology

Biological Plasticity Rescues Target Activity in CRISPR Knockouts

A. H. Smits, F. Ziebell, G. Joberty, N. Zinn, W. F. Mueller, S. Clauder-Münster, D. Eberhard, M. Fälth Savitski, P. Grandi, P. Jakob, A.-M. Michon, H. Sun, K. Tessmer, T. Bürckstümmer, M. Bantscheff, , W. Huber

The paper quantifies residual protein expression in CRISPR-Cas9 knockouts using RNA-seq and SPS-MS3, identifying mechanisms of partial protein preservation and functional retention.

bioRxiv · Jul 26, 2019Bioengineering