Author

T. Bürckstümmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. H. Smits· 1 shared A.-M. Michon· 1 shared D. Eberhard· 1 shared F. Ziebell· 1 shared G. Drewes· 1 shared G. Joberty· 1 shared H. Sun· 1 shared K. Tessmer· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

A. H. Smits

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2 papers

Recent·Most cited

Cell BiologybioRxivOct 13, 2020

AAV Capsid Chimeras with Enhanced Infectivity reveal a core element in the AAV Genome critical for both Cell Transduction and Capsid Assembly

L. Viney, T. Bürckstümmer, M. Mietzsch…·M. Agbandje-McKenna

This paper develops an AAV chimera, AAV-XV, with enhanced T cell transduction efficiency at lower doses and identifies a critical genomic region for both capsid assembly and transduction.

DOI 10.1128/jvi.02023-20

humanexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivJul 26, 2019

Biological Plasticity Rescues Target Activity in CRISPR Knockouts

A. H. Smits, F. Ziebell, G. Joberty…·W. Huber

The paper quantifies residual protein expression in CRISPR-Cas9 knockouts using RNA-seq and SPS-MS3, identifying mechanisms of partial protein preservation and functional retention.

DOI 10.1038/s41592-019-0614-5

humanbulk RNA-seq

𝕏 PostBluesky