Author

G. E. Gonzalez-Paez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Organism:bacteria (other)· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

D. W. Wolan· 2 shared B. F. Cravatt· 1 shared B. Hill-Payne· 1 shared E. J. Roncase· 1 shared J. Eberhardt· 1 shared J. H. Xu· 1 shared J. O. Castellon· 1 shared K. M. Backus· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

D. W. Wolan

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2 papers

Recent·Most cited

Integrative x-ray structure and molecular modeling for the rationalization of procaspase-8 inhibitor potency and selectivity

J. H. Xu, J. Eberhardt, B. Hill-Payne, G. E. Gonzalez-Paez, J. O. Castellon, B. F. Cravatt, S. Forli, D. W. Wolan, K. M. Backus

The paper uses X-ray crystallography and molecular modeling to study how a small-molecule inhibitor binds to and inhibits procaspase-8, revealing structural changes and key interactions.

bioRxiv · Aug 5, 2019Biochemistry

X-ray structures of two active secreted Bacteroides thetaiotaomicron C11 proteases in complex with peptide-based inhibitors

E. J. Roncase, G. E. Gonzalez-Paez, D. W. Wolan

The paper determines the X-ray structures of two secreted C11 proteases from Bacteroides thetaiotaomicron in complex with peptide inhibitors, revealing key active-site interactions and substrate preferences.

bioRxiv · Jan 17, 2019Biochemistry