Antibiotic usage promotes the evolution of resistance against gepotidacin, a novel multi-targeting drug
P. Szili, G. Draskovits, T. Revesz, F. Bogar, D. Balogh, T. Martinek, L. Daruka, R. Spohn, B. M. Vasarhelyi, M. Czikkely, B. Kintses, G. Grezal, G. Ferenc, C. Pal, A. Nyerges
This study shows that antibiotic use promotes resistance evolution against gepotidacin, a multi-targeting antibiotic, through mutations that also confer resistance to fluoroquinolones.
bioRxiv · Dec 13, 2018Microbiology