Author

M. Czikkely

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Pal· 3 shared A. Nyerges· 2 shared D. Balogh· 2 shared P. Szili· 2 shared B. Kintses· 1 shared B. M. Vasarhelyi· 1 shared C. J. Gregg· 1 shared C. MacLean· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

C. Pal

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Author profile →

3 papers

Recent·Most cited

The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence

P. K. Jangir, L. Ogunlana, P. Szili, M. Czikkely, E. J. Stevens, Y. Yang, Q. Yang, Y. Wang, C. Pal, T. R. Walsh, C. MacLean

This study shows that colistin resistance in E. coli increases resistance to host antimicrobial peptides and virulence, highlighting risks of therapeutic AMP use.

bioRxiv · Feb 12, 2022Microbiology

Improved bacterial recombineering by parallelized protein discovery

T. M. Wannier, A. Nyerges, H. Kuchwara, M. Czikkely, D. Balogh, G. T. Filsinger, N. C. Borders, C. J. Gregg, M. J. Lajoie, X. Rios, C. Pal, G. M. Church

This paper introduces a high-throughput method called SEER to discover efficient single-stranded DNA-annealing proteins (SSAPs) for bacterial recombineering, identifying variants that significantly improve genome editing efficiency in multiple bacterial species.

Proceedings of the National Academy of Sciences · May 28, 2020Peer-reviewedMicrobiology

Antibiotic usage promotes the evolution of resistance against gepotidacin, a novel multi-targeting drug

P. Szili, G. Draskovits, T. Revesz, F. Bogar, D. Balogh, T. Martinek, L. Daruka, R. Spohn, B. M. Vasarhelyi, M. Czikkely, B. Kintses, G. Grezal, G. Ferenc, C. Pal, A. Nyerges

This study shows that antibiotic use promotes resistance evolution against gepotidacin, a multi-targeting antibiotic, through mutations that also confer resistance to fluoroquinolones.

bioRxiv · Dec 13, 2018Microbiology