Author

G. Giacomelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:C. elegans· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

M. Bramkamp· 5 shared F. Peng· 2 shared H. Feddersen· 2 shared M. Weiss· 2 shared A. Haouz· 1 shared A. Imhof· 1 shared A. M. Wehenkel· 1 shared A. Schmidt· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersMicrobiology

M. Bramkamp

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5 papers

Recent·Most cited

Deletion of SMC renders FtsK essential in Corynebacterium glutamicum

F. Peng, G. Giacomelli, F. M. Meyer, M. Linder, M. Haak, C. Rueckert-Reed, M. Weiss, J. Kalinowski, M. Bramkamp

This paper shows that in Corynebacterium glutamicum, deletion of SMC makes FtsK essential for chromosome segregation, as FtsK compensates for SMC loss by extending its activity at the septum.

bioRxiv · Oct 14, 2023 · PreprintMicrobiology

A novel nuclease is the executing part of a bacterial plasmid defense system

M. Weiss, G. Giacomelli, M. Ben Assaya, F. Grundt, A. Haouz, F. Peng, S. Petrella, A. M. Wehenkel, M. Bramkamp

The paper identifies MksG as a novel nuclease in the MksBEFG plasmid defense system of Corynebacterium glutamicum, showing it degrades plasmid DNA and is regulated by DivIVA.

bioRxiv · Oct 6, 2022 · PreprintMicrobiology

The CTPase activity of ParB acts as a timing mechanism to control the dynamics and function of prokaryotic DNA partition complexes

M. Osorio-Valeriano, F. Altegoer, C. K. Das, W. Steinchen, G. Panis, L. Connolley, G. Giacomelli, H. Feddersen, L. Corrales-Guerrero, P. Giammarinaro, J. Hanssmann, M. Bramkamp, P. H. Viollier, S. Murray, L. V. Schäfer, , M. Thanbichler

This study identifies how ParB's CTPase activity regulates DNA partition complex dynamics and function by controlling clamp sliding time and spreading.

bioRxiv · May 5, 2021Microbiology

Lsr2 is a nucleoid-associated protein that exerts pleiotropic effects on mycobacterial cellular processes

M. Kolodziej, D. Trojanowski, K. Bury, J. Holowka, M. Pasciak, W. Matysik, H. Kakolewska, H. Feddersen, G. Giacomelli, M. Bramkamp, I. Konieczny, J. Zakrzewska-Czerwinska

This study shows that Lsr2 is essential for mycobacterial chromosome structure and cell envelope properties, with implications for drug development.

bioRxiv · Apr 27, 2020 · PreprintMicrobiology

Chromosome organization by a conserved condensin-ParB system in the actinobacterium Corynebacterium glutamicum

K. Boehm, G. Giacomelli, A. Schmidt, A. Imhof, R. Koszul, M. Marbouty, M. Bramkamp

This study investigates the role of ParB and condensin complexes in chromosome organization in Corynebacterium glutamicum, revealing distinct functions for different condensin paralogs.

bioRxiv · May 25, 2019Microbiology