Author

G. Guella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Astolfi· 1 shared A. Boldrini· 1 shared A. Del Piano· 1 shared A. Ianeselli· 1 shared A. Peretti· 1 shared A. Quattrone· 1 shared A. Romanel· 1 shared B. Vignoli· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Astolfi

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Author profile →

2 papers

Recent·Most cited

One-shot analysis of translated mammalian lncRNAs with AHARIBO

L. Minati, C. Firrito, A. Del Piano, A. Peretti, S. Sidoli, D. Peroni, R. Belli, F. Gandolfi, A. Romanel, P. Bernabo, J. Zasso, A. Quattrone, G. Guella, F. Lauria, G. Viero, M. Clamer

The paper introduces AHARIBO, a method to identify ribosome-associated and peptide-producing lncRNAs, and applies it to mouse embryonic stem cells during neuronal differentiation to distinguish lncRNAs as ribosome sponges or micropeptide encoders.

bioRxiv · Apr 20, 2020Cell Biology

PHARMACOLOGICAL PROTEIN INACTIVATION BY TARGETING FOLDING INTERMEDIATES

G. Spagnolli, T. Massignan, A. Astolfi, S. Biggi, P. Brunelli, M. Libergoli, A. Ianeselli, S. Orioli, A. Boldrini, L. Terruzzi, G. Maietta, M. Rigoli, N. Lopez Lorenzo, L. C. Fernandez, L. Tosatto, , E. Biasini

The paper discovers non-native metastable states in protein folding pathways and develops a novel drug discovery approach, PPI-FIT, to target these intermediates to lower protein expression.

bioRxiv · Mar 31, 2020 · PreprintBiochemistry