Metformin chlorination byproducts in drinking water exhibit marked toxicity to nematode worms, human cells, and mice
R. Zhang, Y. He, L. Yao, J. Chen, S. Zhu, X. Rao, P. Tang, J. You, L. Zhang, G. Hua, F. Ju, L. Wu
This study shows that metformin chlorination byproducts are toxic to nematodes, human cells, and mice, and identifies boiling and activated carbon as effective removal methods.
bioRxiv · Jul 18, 2020 · PreprintPharmacology & Toxicology