X. Rao

Dysregulation of mitochondrial function by PLK1-mediated PDHA1 phosphorylation promotes Cr(VI)-associated lung cancer progression

This study shows that PLK1-mediated PDHA1 phosphorylation impairs mitochondrial function and promotes Cr(VI)-induced lung cancer progression by disrupting energy metabolism and apoptosis.

Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling

This study shows that PLK1 phosphorylates AHR in LUAD, promoting metastasis through DIO2-TH signaling.

Genome-scale mRNA transcriptomic insights into the mature growth dynamic of Cigar tobacco leaves

This study uses transcriptomic analysis to examine gene expression changes in cigar leaves at different growth stages, identifying key pathways and regulatory networks associated with maturity.

Metformin chlorination byproducts in drinking water exhibit marked toxicity to nematode worms, human cells, and mice

This study shows that metformin chlorination byproducts are toxic to nematodes, human cells, and mice, and identifies boiling and activated carbon as effective removal methods.

The role of HMGB1 in invasive Candida albicans infection

This study investigates HMGB1's role in invasive C. albicans infection and shows that EP reduces HMGB1 levels, tissue damage, and mortality in infected mice.

β-lactam Antibiotics Stimulate the Pathogenicity of Methicillin-resistant Staphylococcus aureus Via SarA-controlled Tandem Lipoprotein Expression

This study shows that β-lactam antibiotics increase MRSA pathogenicity by upregulating the tlpps gene cluster via SarA, leading to enhanced inflammation and infection severity.

Faster carbon accumulation in global forest soils

The paper introduces a new method to estimate soil organic carbon stocks by accounting for soil volume changes, revealing an additional carbon sink in global forests.