Author

G. J. Weiss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Muralidharan· 2 shared A. Jensen-Smith· 1 shared A. Parikh· 1 shared B. Shen· 1 shared E. Choi· 1 shared G. T. Motz· 1 shared K. E. McGinness· 1 shared K. R. Whiteman· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

S. Muralidharan

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2 papers

Recent·Most cited

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel Cell Carcinoma

S. Muralidharan, T. Kervarrec, G. J. Weiss, M. Samimi

This study investigates GPC3 expression in Merkel Cell Carcinoma (MCC) and finds it is more common in MCPyV-negative tumors and linked to worse patient outcomes.

bioRxiv · Feb 6, 2022Cancer Biology

BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved antitumor activity

T. L. Hickman, E. Choi, K. R. Whiteman, S. Muralidharan, T. Pai, T. Johnson, A. Parikh, T. Friedman, M. Gilbert, B. Shen, L. Barron, K. E. McGinness, S. A. Ettenberg, G. T. Motz, G. J. Weiss, A. Jensen-Smith

This paper evaluates BOXR1030, a CAR T cell therapy co-expressing GPC3-targeted CAR and GOT2, showing enhanced T cell metabolism and improved antitumor activity in preclinical models.

bioRxiv · Nov 17, 2021 · PreprintCancer Biology