The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis
A. Wyss, T. Raselli, G. Schmelczer, G. Klinke, N. Perkins, M. Hersberger, M. R. Spalinger, K. Atrott, S. Lang, I. Frey-Wagner, M. Scharl, A. W. Sailer, O. Pabst, G. Rogler, B. Misselwitz
This study shows that the EBI2-7,25-dihydroxycholesterol axis is induced in colitis and promotes lymphoid structure accumulation during homeostasis and inflammation.
bioRxiv · Sep 24, 2018Immunology