Drug-like small molecules that inhibit expression of the oncogenic microRNA-21
M. D. Shortridge, B. Chaubey, H. J. Zhang, T. Pavelitz, G. L. Olsen, G. Calin, G. Varani
This study identifies small molecules that inhibit miR-21 maturation, showing specific anti-proliferative effects in cancer cells without affecting kinases or receptors.
bioRxiv · Apr 30, 2022Biochemistry