Author

G. Lenoir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Stock· 2 shared J. A. Lyons· 2 shared P. Nissen· 2 shared T. Dieudonne· 2 shared C. Jaxel· 1 shared C. Montigny· 1 shared F. Kummerer· 1 shared K. Lindorff-Larsen· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. Stock

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Activation and substrate specificity of the human P4-ATPase ATP8B1

T. Dieudonne, F. Kummerer, M. Juknaviciute Laursen, C. Stock, R. Kock Flygaard, S. Khalid, G. Lenoir, J. A. Lyons, K. Lindorff-Larsen, P. Nissen

This study presents cryo-EM structures and functional analysis of the human ATP8B1-CDC50A complex, revealing its mechanism of action, substrate specificity, and regulation by phosphoinositides.

Nature Communications · Nov 18, 2023Peer-reviewedBiochemistry

Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders

T. Dieudonne, S. A. Herrera, M. J. Laursen, M. Lejeune, C. Stock, K. Slimani, C. Jaxel, J. A. Lyons, C. Montigny, T. G. Pomorski, P. Nissen, G. Lenoir

This study investigates the autoinhibition and regulation of ATP8B1, a lipid flippase, through functional studies and cryo-EM structure analysis, revealing the role of phosphoinositides and terminal segments in its activity.

bioRxiv · Nov 3, 2021Biochemistry