Free-fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
M. L. Croze, M. Flisher, A. Guillaume, C. Tremblay, G. M. Noguchi, S. Granziera, K. Vivot, V. C. Castillo, S. A. Campbell, J. Ghislain, M. O. Huising, V. Poitout
This study shows that GPR120 activation in delta cells inhibits somatostatin release, thereby enhancing insulin and glucagon secretion in mice.
bioRxiv · Jul 17, 2020Cell Biology