Molecular determinants of SR-B1-dependent Plasmodium sporozoite entry into hepatocytic cells.
A.-C. Langlois, G. Manzoni, L. Vincensini, R. Coppee, C. Marinach, M. Guerin, T. Huby, V. Carriere, F.-L. Cosset, M. Dreux, E. Rubinstein, O. Silvie
This study identifies structural determinants of SR-B1 required for Plasmodium sporozoite entry into hepatocytes using chimeric mouse/human SR-B1 constructs and structure-guided analysis.
bioRxiv · Mar 16, 2020Microbiology