Microbiota-derived metabolites inhibit Salmonella virulent subpopulation development by acting on single-cell behaviors
A. M. Hockenberry, G. Micali, G. Takacs, J. Weng, W.-D. Hardt, M. Ackermann
This study shows microbiota-derived short-chain fatty acids reduce Salmonella virulent subpopulation frequency by slowing their growth, not by repressing SPI-1 expression at the single-cell level.
bioRxiv · Feb 14, 2021Microbiology