Author

G. N. Cholico

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

R. Nault· 2 shared T. R. Zacharewski· 2 shared K. A. Fader· 1 shared N. A. Zacharewski· 1 shared R. R. Fling· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersPharmacology & Toxicology

R. Nault

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2 papers

Recent·Most cited

Genome-wide ChIPseq analysis of AhR, COUP-TF, and HNF4 enrichment in TCDD-treated mouse liver

G. N. Cholico, R. Nault, T. R. Zacharewski

This study identifies genomic binding sites and gene expression changes of AhR, COUP-TFII, and HNF4 in TCDD-treated mouse liver, revealing their interactions in liver function and differentiation.

bioRxiv · Jun 18, 2021Pharmacology & Toxicology

Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic β-oxidation

G. N. Cholico, R. R. Fling, N. A. Zacharewski, K. A. Fader, R. Nault, T. R. Zacharewski

This study shows TCDD induces a futile cycle in hepatic fatty acid metabolism by repressing β-oxidation genes and increasing octenoyl-CoA, which inhibits ECHS1 activity.

bioRxiv · Jan 21, 2021Pharmacology & Toxicology