Simultaneous analysis of pMHC binding and reactivity unveils virus-specific CD8 T cell immunity to a concise epitope set
N. P. Kristensen, E. Dionisio, A. K. Bentzen, T. Tamhane, J. S. Kemming, G. Nos, L. F. Voss, U. K. Hansen, G. M. Lauer, S. R. Hadrup
The paper identifies a concise set of 137 virus-specific CD8 T cell epitopes recognized by human T cells, with 84% showing prevalent reactivity and associations with effector and memory phenotypes.
bioRxiv · Nov 6, 2023Immunology