Author

G. P. Sugerman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

M. K. Rausch· 6 shared S. Kakaletsis· 3 shared M. Malinowski· 2 shared M. Mathur· 2 shared S. H. Parekh· 2 shared T. A. Timek· 2 shared T. Jazwiec· 2 shared W. D. Meador· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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6 shared papersBioengineering

M. K. Rausch

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6 papers

Recent·Most cited

Elasticity of Whole Blood Clots Measured via Volume Controlled Cavity Expansion

H. M. Varner, G. P. Sugerman, M. K. Rausch, T. Cohen

This paper measures the mechanical properties of whole blood clots using Volume Controlled Cavity Expansion and finds that a 1-term Ogden model captures their nonlinear elasticity, with a significant decrease in shear modulus after 2 days of storage.

Journal of the Mechanical Behavior of Biomedical Materials · Jul 1, 2023Peer-reviewedBioengineering

Untangling the mechanisms of pulmonary hypertension-induced right ventricular stiffening in a large animal model

S. Kakaletsis, M. Malinowski, M. Mathur, G. P. Sugerman, J. J. Luci, C. Snider, T. Jazwiec, M. R. Bersi, T. A. Timek, M. K. Rausch

This study investigates the mechanisms of right ventricular stiffening in pulmonary hypertension using a large animal model, finding that myocardial stiffness is the primary contributor.

bioRxiv · Apr 3, 2023 · PreprintPhysiology

Sex- and Age-dependent Skin Mechanics - A Detailed Look in Mice

C.-Y. Lin, G. P. Sugerman, S. Kakaletsis, W. D. Meador, A. B. Tepole, M. K. Rausch

This study investigates age- and sex-dependent changes in skin mechanics in mice using mechanical testing, histology, collagen assays, and two-photon microscopy, revealing sex differences in stiffness that emerge with age.

bioRxiv · Mar 8, 2023Biophysics

The tricuspid valve also maladapts: A multiscale study in sheep with biventricular heart failure

W. D. Meador, M. Mathur, G. P. Sugerman, M. Malinowski, T. Jazwiec, X. Wang, C. M. Lacerda, T. A. Timek, M. K. Rausch

This study shows tricuspid valves maladapt in a sheep model of heart failure, leading to structural and mechanical changes that may contribute to tricuspid regurgitation.

bioRxiv · Sep 3, 2020 · PreprintBioengineering

A Whole Blood Thrombus Mimic: Constitutive Behavior Under Simple Shear

G. P. Sugerman, S. Kakaletsis, P. Thakkar, A. Chokshi, S. H. Parekh, M. K. Rausch

This paper develops an in-vitro thrombus mimic from whole blood and tests its mechanical behavior under simple shear, finding strain-stiffening and the Ogden model provides the best fit.

bioRxiv · Jul 19, 2020Bioengineering

Toward understanding thrombus fracture: Dissipative phenomena of whole blood clots

G. P. Sugerman, S. H. Parekh, M. K. Rausch

This study identifies and quantifies dissipative mechanisms in whole blood clots under various mechanical tests, revealing phenomena similar to hydrogels that are critical for understanding thrombus fracture.

bioRxiv · Jul 19, 2020 · PreprintBioengineering