Author

G. Refregier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Organism:human· 1

Frequent Co-Authors

A. Barbry· 2 shared C. Genestet· 2 shared C. Guyeux· 2 shared C. Sola· 2 shared E. Hodille· 2 shared E. Westeel· 2 shared F. Ader· 2 shared F. Massol· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

A. Barbry

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4 papers

Recent·Most cited

TB-annotator: a scalable web application that allows in-depth analysis of very large sets of publicly available Mycobacterium tuberculosis complex genomes

G. Senelle, C. Guyeux, G. Refregier, C. Sola

TB-annotator provides a scalable web platform for analyzing large Mycobacterium tuberculosis complex genome datasets, offering tools for variant detection and phylogenetic analysis.

bioRxiv · Jun 12, 2023 · PreprintMicrobiology

Mycobacterium tuberculosis genetic features associated with pulmonary tuberculosis severity

C. Genestet, G. Refregier, E. Hodille, R. Zein-Eddine, A. Le Meur, F. Hak, A. Barbry, E. Westeel, J.-L. Berland, A. Engelmann, I. Verdier, G. Lina, F. Ader, S. Dray, L. Jacob, , O. Dumitrescu

This study identifies Mtb genetic features linked to pulmonary tuberculosis severity using whole genome sequencing and genome-wide association analysis.

bioRxiv · May 25, 2022Microbiology

Within-host genetic micro-diversity of Mycobacterium tuberculosis and the link with tuberculosis disease features

C. Genestet, E. Hodille, F. Massol, G. Refregier, A. Barbry, E. Westeel, G. Lina, F. Ader, L. Jacob, S. Dray, J.-L. Berland, S. Venner, O. Dumitrescu

The paper shows that genetic diversity within Mycobacterium tuberculosis isolates from the same patient correlates with TB severity and is driven by adaptation to infection sites.

bioRxiv · Apr 7, 2021 · PreprintMicrobiology

Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in Mycobacterium tuberculosis

G. Refregier, C. Sola, C. Guyeux

The paper analyzes CRISPR-cas locus diversity in Mycobacterium tuberculosis isolates and finds unexpected diversity in spacers and repeats, suggesting alternative evolutionary mechanisms.

bioRxiv · Dec 13, 2019Microbiology