Author

E. Hodille

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

O. Dumitrescu· 4 shared A. Barbry· 3 shared C. Genestet· 3 shared E. Westeel· 3 shared F. Ader· 3 shared G. Lina· 3 shared J.-L. Berland· 3 shared S. Venner· 3 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

O. Dumitrescu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Biochemical and structural characterization of a Class A β-lactamase from Nocardia cyriacigeorgica

J. Feuillard, J. Couston, Y. Benito, E. Hodille, O. Dumitrescu, M. Blaise

This study reports the biochemical characterization and high-resolution crystal structure of a class A β-lactamase from Nocardia cyriacigeorgica, revealing its structural conservation and potential for drug development.

bioRxiv · Oct 2, 2023 · PreprintBiochemistry

Mycobacterium tuberculosis genetic features associated with pulmonary tuberculosis severity

C. Genestet, G. Refregier, E. Hodille, R. Zein-Eddine, A. Le Meur, F. Hak, A. Barbry, E. Westeel, J.-L. Berland, A. Engelmann, I. Verdier, G. Lina, F. Ader, S. Dray, L. Jacob, , O. Dumitrescu

This study identifies Mtb genetic features linked to pulmonary tuberculosis severity using whole genome sequencing and genome-wide association analysis.

bioRxiv · May 25, 2022Microbiology

Within-host genetic micro-diversity of Mycobacterium tuberculosis and the link with tuberculosis disease features

C. Genestet, E. Hodille, F. Massol, G. Refregier, A. Barbry, E. Westeel, G. Lina, F. Ader, L. Jacob, S. Dray, J.-L. Berland, S. Venner, O. Dumitrescu

The paper shows that genetic diversity within Mycobacterium tuberculosis isolates from the same patient correlates with TB severity and is driven by adaptation to infection sites.

bioRxiv · Apr 7, 2021 · PreprintMicrobiology

Rifampicin exposure reveals within-host Mycobacterium tuberculosis diversity in patients with delayed culture conversion

C. Genestet, E. Hodille, A. Barbry, J.-L. Berland, J. Hoffmann, E. Westeel, F. Bastian, M. Guichardant, S. Venner, G. Lina, C. Ginevra, F. Ader, S. Goutelle, O. Dumitrescu, on behalf of the Lyon TB study group

The paper analyzes genetic diversity in Mycobacterium tuberculosis isolates from TB patients with delayed culture conversion, revealing drug-tolerant sub-populations and their potential role in treatment failure.

bioRxiv · May 22, 2020 · PreprintMicrobiology