Effect of Nrf2 Loss on Senescence and Cognition of Tau-Based P301S Mice
R. T. Riordan, R. Wang, Z. Yu, G. Ross, J. Valerio, J. Dimas-Munoz, V. Heredia, K. R. Magnusson, V. Galvan, V. I. Perez
This study investigates how Nrf2 loss affects senescence and cognition in P301S tauopathy mice, finding that Nrf2 protects brain function through mechanisms beyond senescence inhibition.
bioRxiv · Oct 31, 2022Animal Behavior & Cognition